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KMID : 0367419790200040046
Journal of Korean Pediatric Society
1979 Volume.20 No. 4 p.46 ~ p.53
Clinical Observation of Meningococcal Infection
ì°ëùïÙ/Lee, Eui Jung
Abstract
Meningococcal infection; may range from a simple upper respiratory infection to fulminating syste nic diseases such as meningitis, septcemia, endotosin shock and disseminated intravascular coagulation,
This pipe- reports on systemic meningococcal disease which were collected from Department of Ped;at;cs, Yonsei University Medical College, from May, 1953 to April, 1976. Fol,owing results were obtained from this observation:
1. No striking differences were noted between boys(25 cases, and giris(27 cases) in incidence.
2. The most of cases appeared in winter and spring.
3. The clinical features may be summarized as follows: The most common compliants¢¥are fever (60%) and poor responsivess (77%) even coma. The meningeai signs (73%), skin rash (6956, vomiting (65%) and convulsion (42%) are prominent features oe disease.
4. Leukocytosis with neutrophil:a was present in 80% of patients. Leukopenia or normal taunt were noted in 20% of patierts, in the peripheral blood.
5. Ninety percent of patients revealed finding of meningitis on spinal tap. mostly purulent type.
6. Poor prognostic signs include changes of mental state such as coma or semicoma, when there was iro signs of meningitis sn CSF at admissinn, when meningococci was found in blood culture nr y, normal leukocyte ccunt or leukopenia in peripheral blood.
7. The mortality was 21% of patients and the most of expired patients were dead within 48 hours after initiation of thsrapy.
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